Discovering contradicting protein-protein interactions in text

In biomedical texts, contradictions about proteinprotein interactions (PPIs) occur when an author reports observing a given PPI whereas another author argues that very same interaction does not take place: e.g., when author X argues that “protein A interacts with protein B” whereas author Y claims that “protein A does not interact with B”. Of course, merely discovering a potential contradiction does not mean the argument is closed as other factors may have caused the proteins to behave in different ways. We present preliminary work towards the automatic detection of potential contradictions between PPIs from text and an agreement experimental evaluation of our method.